Anti-Histone H2A.Z Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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H2AZ1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-3H9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human Histone H2A.Z
Molecular Weight
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Calculated MW: 14 kDa; Observed MW: 14 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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3015
Uniprot ID
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P0C0S5
Background
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Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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H2AZ; H2A.z; H2A/z; H2A.Z-1