Anti-Hexokinase I (6B8) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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HK1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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6B8-G11-E7
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Purified recombinant human Hexokinase 1 protein fragments expressed in E.coli
Molecular Weight
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Calculated MW: 102 kDa; Observed MW: 102 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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3098
Uniprot ID
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P19367
Background
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Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation.
Research Area
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Cardiovascular
Synonyms
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HK1; Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I