Anti-HEC1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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NDC80
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-3C6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IP: 1/50
Immunogen
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A synthesized peptide derived from human HEC1
Molecular Weight
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Calculated MW: 74 kDa; Observed MW: 74 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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10403
Uniprot ID
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O14777
Background
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Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
Research Area
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Cell Biology
Synonyms
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HEC; HsHec1; hsNDC80; Kinetochore protein Hec1; Kinetochore-associated protein 2; KNTC2; ndc80; TID3