Anti-HDAC8 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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HDAC8
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-4G9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IP: 1/20
Immunogen
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A synthetic peptide of human HDAC8
Molecular Weight
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Calculated MW: 42 kDa; Observed MW: 42 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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55869
Uniprot ID
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Q9BY41
Background
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Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8