Anti-HCN4 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
HCN4
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
IHC: 1/50-1/100
Immunogen
-
Synthetic peptide of human HCN4
Molecular Weight
-
-
Formulation
-
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
-
Liquid
Gene ID
-
10021
Uniprot ID
-
Q9Y3Q4
Background
-
This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.
Research Area
-
Neuroscience
Synonyms
-
SSS2