Anti-Growth Hormone Receptor Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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GHR
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide of human GHR
Molecular Weight
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Calculated MW: 72 kDa; Observed MW: 72 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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2690
Uniprot ID
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P10912
Background
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Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
Research Area
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Signal Transduction
Synonyms
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GHR; Growth hormone receptor; GH receptor; Somatotropin receptor