Anti-GRIK3 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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GRIK3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide of human GRIK3
Molecular Weight
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Calculated MW: 104 kDa; Observed MW: 104 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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2899
Uniprot ID
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Q13003
Background
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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
Research Area
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Synonyms
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glutamate ionotropic receptor kainate type subunit 3; EAA5; GLR7; GLUR7; GluK3; GluR7a