Anti-GNE Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
GNE
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R05-7A8
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IP: 1/20
Immunogen
-
A synthetic peptide of human GLCNE
Molecular Weight
-
Calculated MW: 79 kDa; Observed MW: 75 kDa
Formulation
-
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
-
Liquid
Gene ID
-
10020
Uniprot ID
-
Q9Y223
Background
-
Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development . Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.
Research Area
-
Cardiovascular
Synonyms
-
NM; DMRV; IBM2; Uae1; GLCNE