Anti-Glucose Transporter GLUT4 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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SLC2A4
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Immunogen
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The antiserum was produced against synthesized peptide derived from the N-terminal region of human SLC2A4.
Molecular Weight
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Calculated MW: 55 kDa; Observed MW: 55 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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6517
Uniprot ID
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P14672
Background
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This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
Research Area
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Signal Transduction
Synonyms
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SLC2A4; GLUT4; Solute carrier family 2; facilitated glucose transporter member 4; Glucose transporter type 4; insulin-responsive; GLUT-4