Anti-GLI1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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GLI1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Synthetic peptide of human GLI1
Molecular Weight
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Calculated MW: 118 kDa; Observed MW: 118 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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2735
Uniprot ID
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P08151
Background
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GLI belongs to the Kruppel family of zinc finger proteins that includes three mammalian GLI proteins: GLI1, GLI2, and GLI3. Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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Zinc finger protein GLI1; Glioma-associated oncogene; Oncogene GLI; Zfp5; GLI family zinc finger 1; GLI