Anti-GLI1 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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GLI1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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ZN170
Isotype
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IgG1
Reactivity
Application
Application Details
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IHC: 1/50-1/100
Immunogen
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Human recombinant protein fragment of human GLI1 (NP_005260) produced in E.coli.
Molecular Weight
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-
Formulation
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PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
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Liquid
Gene ID
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2735
Uniprot ID
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P08151
Background
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This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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Zinc finger protein GLI1; Glioma-associated oncogene; Oncogene GLI; Zfp5; GLI family zinc finger 1; GLI