Anti-Geminin Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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GMNN
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-8O-2
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/200
Immunogen
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Recombinant protein of human Geminin
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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51053
Uniprot ID
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O75496
Background
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Inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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Gem; Geminin; GMNN