Anti-GEF H1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ARHGEF2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-3D1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human GEF H1
Molecular Weight
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Calculated MW: 112 kDa; Observed MW: 112 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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9181
Uniprot ID
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Q92974
Background
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Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, and cancer.
Research Area
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Signal Transduction
Synonyms
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ARHG2; ARHGEF2; GEF; GEFH1; Lbcl1; Lfc; LFP40