Anti-GCLM Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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GCLM
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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1Q9-V9-K6
Isotype
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IgG2B/Kappa
Reactivity
Application
Application Details
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WB:1/500-1/1000 IHC-P:1/50-1/100
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 31 kDa; Observed MW:31 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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2730
Uniprot ID
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P48507
Background
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Glutamate-cysteine ligase regulatory subunit is an enzyme that in humans is encoded by the GCLM gene.Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
Research Area
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Neuroscience
Synonyms
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GLCLR