Anti-GAPDH Antibody (2B8), Cy3 Conjugated
Product Information
Downloads & Supports
Target
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GAPDH
Host
Storage
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Store at -20°C/1 year
Clonality
Isotype
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Monoclonal, Mouse IgG1
Reactivity
Application
Application Details
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Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:200, IF 1:200.
Formulation
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Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
Form
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Liquid
Gene ID
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2597
Uniprot ID
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P04406
Background
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glyceraldehyde-3-phosphate dehydrogenase(GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri
Synonyms
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GAPDH