Anti-Gap Junction gamma 2 Protein Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
GJC2
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000
Immunogen
-
Synthetic peptide of human GJC2
Molecular Weight
-
Calculated MW: 47 kDa; Observed MW: 47 kDa
Formulation
-
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
-
Liquid
Gene ID
-
57165
Uniprot ID
-
Q5T442
Background
-
This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.
Research Area
-
Signal Transduction
Synonyms
-
gap junction protein; gamma 2; 47kDa; Cx47; HLD2; GJA12; SPG44; CX46.6; LMPH1C; PMLDAR