Anti-GALC Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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GALC
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Synthetic peptide of human GALC
Molecular Weight
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Calculated MW: 77 kDa; Observed MW: 77 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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2581
Uniprot ID
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P54803
Background
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This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Research Area
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Cardiovascular
Synonyms
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Galactocerebroside beta-galactosidase; Galactosylceramidase; Galactosylceramide beta-galactosidase