Anti-FOXP3 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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FOXP3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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ZN248
Isotype
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IgG2a
Reactivity
Application
Application Details
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IHC: 1/50-1/100
Immunogen
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Full length human recombinant protein of human FOXP3 (NP_001107849) produced in E.coli.
Molecular Weight
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-
Formulation
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PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
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Liquid
Gene ID
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50943
Uniprot ID
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Q9BZS1
Background
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Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.
Research Area
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Cell Biology
Synonyms
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FOXP3; IPEX; JM2; Forkhead box protein P3; Scurfin