Anti-FOXA1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
FOXA1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R08-5L-8
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB：1/500-1/1000
Immunogen
-
Peptide
Molecular Weight
-
Calculated MW: 49 kDa; Observed MW:52 kDa
Formulation
-
Liquid in PBS, Glycerol and BSA
Form
-
Liquid
Gene ID
-
3169
Uniprot ID
-
P55317
Background
-
Forkhead transcription factor (FOXA1) is a pioneering factor in the development of some organs and certain cancers. It opens tight chromatin by interacting with nucleosomal core histones. FOXA1 can bind to cis-acting elements and recruit other transcription factors to induce transcription. FOXA1 is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues, and participates in the development of a variety of endoderm-derived organ systems, such as liver, pancreas, lung and prostate. FOXA1 is related to many diseases and plays a role in hormone-dependent diseases such as breast cancer and prostate cancer.
Research Area
-
Tumor biology
Synonyms
-
HNF3A, TCF3A