Anti-Fos B Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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FOSB
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
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A synthesized peptide derived from human Fos B
Molecular Weight
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Calculated MW: 36 kDa; Observed MW: 38,48 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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2354
Uniprot ID
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P53539
Background
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FosB interacts with Jun proteins enhancing their DNA binding activity. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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G0/G1 switch regulatory protein 3; G0S3; Protein fosB; GOSB; Oncogene FOSB; Activator protein 1