Anti-FMO2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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FMO2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Fusion protein of human FMO2
Molecular Weight
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Calculated MW: 61 kDa; Observed MW: 61 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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2327
Uniprot ID
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Q99518
Background
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This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants.
Research Area
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Signal Transduction
Synonyms
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flavin containing dimethylaniline monoxygenase 2; FMO1B1