Anti-FLAP Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ALOX5AP
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R02-8D6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human FLAP
Molecular Weight
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Calculated MW: 18 kDa; Observed MW: 18 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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241
Uniprot ID
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P20292
Background
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Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Research Area
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Synonyms
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ALOX 5AP; ALOX5 AP; ALOX5AP; FLAP