Anti-FHIT Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
FHIT
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R08-8I2
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000
Immunogen
-
A synthesized peptide derived from human FHIT
Molecular Weight
-
Calculated MW: 17 kDa; Observed MW: 17 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
2272
Uniprot ID
-
P49789
Background
-
FHIT (fragile histidine triad) cleaves adenosine 5' PPP 5' A to yield AMP and ADP. Alterations and deletions of the FHIT gene are strongly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT may act as a tumor suppressor. FHIT physically associates with ubiquitin conjugating enzyme 9.
Research Area
-
-
Synonyms
-
AP3A hydrolase; AP3Aase; Dinucleosidetriphosphatase; FRA3B