Anti-FGFR1(R576W Mutant) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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FGFR1, BFGFR, CD331, CEK, FGFBR, FLG
Host
Storage
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Store at -20°C. Avoid repeated freezing and thawing
Clonality
Clone Number
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6Z7-F2-P5
Isotype
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IgG
Reactivity
Application
Application Details
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ELISA: 1/1000-1/2000 WB: 1/500-1/1000 IHC-P: 1/50-1/100
Immunogen
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A synthetic peptide from the internal region of FGFR1 which includes the mutation of R576W, human origin.
Formulation
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PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
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Liquid
Uniprot ID
-
Background
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The protein FGFR1 is highly conserved between members and throughout evolution. This particular family member of FGFR1 binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations of FGFR1 protein have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome.
Research Area
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Cardiovascular
Synonyms
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FGFR1, BFGFR, CD331, CEK, FGFBR, FLG