Anti-FGF19 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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FGF19
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-2M8
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human FGF19
Molecular Weight
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Calculated MW: 24 kDa; Observed MW: 36 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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9965
Uniprot ID
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O95750
Background
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Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB.
Research Area
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Signal Transduction
Synonyms
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FGF15; FGF19; Fibroblast growth factor 15; Fibroblast growth factor 19