Anti-FGF 22 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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FGF22
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
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Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/200 IF: 1/50-1/200
Immunogen
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Synthetic peptide corresponding to Human FGF 22.
Molecular Weight
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Calculated MW: 20kDa
Formulation
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1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
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Liquid
Gene ID
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27006
Uniprot ID
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Q9HCT0
Background
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Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. Fibroblast growth factor- 22 (FGF-22) is a secreted protein whose gene is localized to human chromosome 19p13.3. FGF-22 is expressed preferentially in the inner root sheath of the hair follicle, suggesting that it is important in hair development.
Research Area
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Synonyms
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Fibroblast growth factor 22; FGF-22; FGF22; UNQ2500/PRO5800