Anti-Fbxw7 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
FBXW7
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R05-4U-4
Isotype
-
IgG
Reactivity
Application
Application Details
-
IHC: 1/100-1/200
Immunogen
-
A synthesized peptide derived from human Fbxw7
Formulation
-
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
-
Liquid
Gene ID
-
55294
Uniprot ID
-
Q969H0
Background
-
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:22748924, PubMed:17434132, PubMed:26976582, PubMed:28727686, PubMed:35395208).
Research Area
-
Cell Biology
Synonyms
-
FBXW7;FBW7 ;FBX30;SEL10 ;F-box/WD repeat-containing protein 7;F-box protein FBX30;SEL-10;hCdc4