Anti-Estrogen Receptor alpha Rabbit Monoclonal Antibody

Anti-Estrogen Receptor alpha Rabbit Monoclonal Antibody
Anti-Estrogen Receptor alpha Rabbit Monoclonal Antibody
Anti-Estrogen Receptor alpha Rabbit Monoclonal Antibody
Anti-Estrogen Receptor alpha Rabbit Monoclonal Antibody
Anti-Estrogen Receptor alpha Rabbit Monoclonal Antibody
Anti-Estrogen Receptor alpha Rabbit Monoclonal Antibody

Anti-Estrogen Receptor alpha Rabbit Monoclonal Antibody

Rabbit IgG Monoclonal for ESR1 detection, Test with WB, IHC-F, IHC-P, ICC/IF, IP, ChIP in Human

Reactivity
  • Human
Application
  • WB
  • IHC-F
  • IHC-P
  • ICC
  • IF
  • IP
  • ChIP
Host
  • Rabbit
Catalog Number
    ABXB60915
$370.00

Shipping To:
United States

Product Information

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Target
    ESR1
Host
  • Rabbit
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    R05-1E4
Isotype
    IgG
Reactivity
  • Human
Application
  • WB
  • IHC-F
  • IHC-P
  • ICC
  • IF
  • IP
  • ChIP
Application Details
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 ChIP: 1/20
Immunogen
    A synthetic peptide of human Estrogen Receptor alpha
Molecular Weight
    Calculated MW: 66 kDa; Observed MW: 66 kDa
Formulation
    50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
    Liquid
Gene ID
    2099
Uniprot ID
    P03372
Background
    ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.
Research Area
    Signal Transduction
Synonyms
    ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha
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Product Image

Western blot analysis of Estrogen Receptor alpha in K562, Hela lysates using Estrogen Receptor alpha antibody.
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Estrogen Receptor alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunocytochemistry analysis of Estrogen Receptor alpha (green) in MCF-7 using Estrogen Receptor alpha antibody,and DAPI(blue)