Anti-ERBB2(D769H Mutant) Mouse Monoclonal Antibody

Anti-ERBB2(D769H Mutant) Mouse Monoclonal Antibody
Anti-ERBB2(D769H Mutant) Mouse Monoclonal Antibody
Anti-ERBB2(D769H Mutant) Mouse Monoclonal Antibody
Anti-ERBB2(D769H Mutant) Mouse Monoclonal Antibody

Anti-ERBB2(D769H Mutant) Mouse Monoclonal Antibody

Mouse IgG Monoclonal for ERBB2,HER2,Neu,c-Neu detection, Test with WB, IHC-P, ELISA in Vertebrates

Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ELISA
Host
  • Mouse
Catalog Number
    ABXB07318
$680.00

Shipping To:
United States

Product Information

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Target
    ERBB2,HER2,Neu,c-Neu
Host
  • Mouse
Storage
    Store at -20°C. Avoid repeated freezing and thawing
Clonality
  • Monoclonal
Clone Number
    7Z5-K7-U6
Isotype
    IgG
Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ELISA
Application Details
    ELISA: 1/1000-1/2000 WB: 1/500-1/1000 ICC/IF: 1/25-1/50
Immunogen
    A synthetic peptide from the internal region of ERBB2 which includes the mutation of D769H, human origin.
Formulation
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
    Liquid
Uniprot ID
    ­
Background
    The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant tumors, especially with breast cancers. The expression level of Her2 is an important criteria in clinic evaluating of the progression of breast cancer.
Research Area
    Tags & Cell Markers
Synonyms
    ERBB2,HER2,Neu,c-Neu
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Product Image

Western blot analysis of recombinant ERBB2(D769H) and wild type proteins. Purified His-tagged ERBB2(D769H) protein (lane 1) and corresponding wild type protein (lane 2) were blotted with Anti-ERBB2(D769H) monoclonal.
Immunofluorescence of cells expressing ERBB2 proteins with Anti-ERBB2(D769H). HEK293T cells were transfected with pCDNA3-GFP-ERBB2 (WT) plasmid (left column) or pCDNA3-GFP-ERBB2(D769H) plasmid (right column), then fixed and stained with Anti-ERBB2(D769H) monoclonal.