Anti-EPHA2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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EPHA2
Host
Storage
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Store at -20°C to -80°C for 12 months in lyophilized form.
Clonality
Clone Number
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R08-1H-7
Isotype
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IgG
Reactivity
Application
Application Details
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FC: 1/50-1/100 ELISA: 1/10000
Immunogen
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Recombinant human EPHA2 protein
Molecular Weight
-
-
Formulation
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Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Form
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Lyophilized
Gene ID
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1969
Uniprot ID
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P29317
Background
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This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.
Research Area
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Cardiovascular
Synonyms
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EPHA2; ECK; Ephrin type-A receptor 2; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK