Anti-Endothelin 1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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EDN1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Immunogen
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The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1.
Molecular Weight
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Calculated MW: 24 kDa; Observed MW: 24 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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1906
Uniprot ID
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P05305
Background
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The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
Research Area
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Signal Transduction
Synonyms
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EDN1; Endothelin-1; Preproendothelin-1; PPET1