Anti-eIF5A Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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EIF5A
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-3F9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Immunogen
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A synthetic peptide of human eIF5A
Molecular Weight
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Calculated MW: 17 kDa; Observed MW: 17 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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1984
Uniprot ID
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P63241
Background
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mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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EIF-5A; EIF5A1; eIF5AI; Eukaryotic initiation factor 5A