Anti-EGFR(G863D Mutant) Mouse Monoclonal Antibody

Anti-EGFR(G863D Mutant) Mouse Monoclonal Antibody
Anti-EGFR(G863D Mutant) Mouse Monoclonal Antibody
Anti-EGFR(G863D Mutant) Mouse Monoclonal Antibody
Anti-EGFR(G863D Mutant) Mouse Monoclonal Antibody

Anti-EGFR(G863D Mutant) Mouse Monoclonal Antibody

Mouse Monoclonal for EGFR,HER1,ERBB1 detection, Test with WB, IHC-P, ICC/IF, ELISA in Vertebrates

Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ICC
  • IF
  • ELISA
Host
  • Mouse
Catalog Number
    ABXB07311
$680.00

Shipping To:
United States

Product Information

Downloads & Supports

Target
    EGFR,HER1,ERBB1
Host
  • Mouse
Storage
    Store at -20°C. Avoid repeated freezing and thawing
Clonality
  • Monoclonal
Clone Number
    6A1-U2-O8
Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ICC
  • IF
  • ELISA
Application Details
    ELISA: 1/1000-1/5000,WB: 1/1000-1/5000,IHC-P: 1/50-1/100
Immunogen
    A synthetic peptide from the internal region of EGFR which includes the mutation of G863D, human origin.
Formulation
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
    Liquid
Uniprot ID
    ­
Background
    EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLC gamma-PKC and STATs modules. Defects in EGFR are associated with lung cancer (LNCR).
Research Area
    Signal Transduction
Synonyms
    EGFR,HER1,ERBB1
MSDSProtocolsRequest COAAlgent Product GuaranteeNeed support?

Product Image

Western blot analysis of recombinant EGFR(G863D) and wild type proteins.Purified His-tagged EGFR(G863D) protein (amino acid 702-987) and corresponding wild type protein were blotted with anti-EGFR(G863D) mouse monoclonal. Proteins loading were blotted with anti-His-tag monoclonal.
Immunofluorescence of cells expressing EGFR proteins with anti-EGFR(G863D).HEK293T cells were transfected with pCDNA3-GFP-EGFR (WT) plasmid (left column) or pCDNA3-GFP-EGFR(G863D) plasmid (right column), then fixed and stained with anti-EGFR(G863D) monoclonal.