Anti-EBF3 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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EBF3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human EBF3
Molecular Weight
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Calculated MW: 65 kDa; Observed MW: 65 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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253738
Uniprot ID
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Q9H4W6
Background
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This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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EBF transcription factor 3; COE3; OE-2; EBF-3; HADDS; O/E-2