Anti-EAR2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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NR2F6
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide corresponding to Human EAR2.
Molecular Weight
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Calculated MW: 43kDa
Formulation
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1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
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Liquid
Gene ID
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2063
Uniprot ID
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P10588
Background
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EAR2 (v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2)protein binds a cis enhancer element (TGACCT motif) upstream of the reningene and represses renin gene transcription. EAR2 also contributes togonadotropin-dependent derepression of LHR promoter activity in granulosacells. EAR2 mRNA is abundant in the liver, and EAR2 protein localizes to thenucleus of As4.1 cells.
Research Area
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-
Synonyms
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Nuclear receptor subfamily 2 group F member 6; V-erbA-related protein 2; EAR-2; NR2F6; EAR2; ERBAL2