Anti-DUSP19 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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DUSP19
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/200 IF: 1/50-1/200
Immunogen
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Synthetic peptide corresponding to Human DUSP19.
Molecular Weight
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Calculated MW: 24kDa
Formulation
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1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
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Liquid
Gene ID
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142679
Uniprot ID
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Q8WTR2
Background
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Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The stress-activated protein kinase (SAPK) pathway-regulating phosphatase 1 (SKRP1) binds to MAP kinase MKK-7 to regulate JNK.
Research Area
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Synonyms
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Dual specificity protein phosphatase 19; Dual specificity phosphatase TS-DSP1; Low molecular weight dual specificity phosphatase 3; LMW-DSP3; Protein phosphatase SKRP1; Stress-activated protein kinase pathway-regulating phosphatase 1; SAPK pathway-regulating phosphatase 1; DUSP17; LMWDSP3; SKRP1; DUSP19