Anti-DNAM1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
CD226
Host
Storage
-
Store at -20°C to -80°C for 12 months in lyophilized form.
Clonality
Clone Number
-
R06-4Q-4
Isotype
-
IgG
Reactivity
Application
Application Details
-
FC: 1/50-1/100 ELISA: 1/10000
Immunogen
-
Recombinant human DNAM-1 protein
Molecular Weight
-
-
Formulation
-
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Form
-
Lyophilized
Gene ID
-
10666
Uniprot ID
-
Q15762
Background
-
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.
Research Area
-
Immunology
Synonyms
-
CD226; DNAM1; CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD antigen CD226