Anti-DNA-RNA Hybrid [S9.6] Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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Isotype
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IgG2a
Reactivity
Application
Application Details
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IF: 1/50-1/200 IP: 1/50-1/300 ChIP: 1/20
Immunogen
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ΦX174 bacteriophage-derived synthetic DNA/RNA
Molecular Weight
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-
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA, pH 7.3.
Form
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Liquid
Gene ID
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Uniprot ID
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Background
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The DNA-RNA hybrids are a natural occurrence within eukaryotic cells and their level are high at sites of high transcriptional activity.They are non-canonical nucleic acid structures with transcriptional regulatory functions. Their presence is reported to predispose a locus to chromosomal breakage. The S9.6 monoclonal antibody recognizes DNA-RNA hybrids (also known as R-loops) and does not bind to single or double stranded DNA.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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DNA-RNA hybrid; RNA/DNA hybrid