Anti-DKK3 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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DKK3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-8G7
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IP: 1/20
Immunogen
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Recombinant protein of human Dkk3
Molecular Weight
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Calculated MW: 38 kDa; Observed MW: 70 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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27122
Uniprot ID
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Q9UBP4
Background
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Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.
Research Area
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Signal Transduction
Synonyms
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DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3