Anti-DIRAS3 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
DIRAS3
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000
Immunogen
-
Fusion protein of human DIRAS3
Molecular Weight
-
Calculated MW: 26 kDa; Observed MW: 26 kDa
Formulation
-
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
-
Liquid
Gene ID
-
9077
Uniprot ID
-
O95661
Background
-
This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex.
Research Area
-
-
Synonyms
-
DIRAS family GTPase 3; ARHI; NOEY2