Anti-DIAPH1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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DIAPH1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R02-6J4
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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A synthesized peptide derived from human DIAPH1
Molecular Weight
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Calculated MW: 141 kDa; Observed MW: 155 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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1729
Uniprot ID
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O60610
Background
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Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor.
Research Area
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Cell Biology
Synonyms
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DIAPH1; DFNA1; DIA1; DIAP1; DIAPH1; DRF1; hDIA1; LFHL1