Anti-Desmin Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
DES
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
1A2-8B10-5G9
Isotype
-
IgG1
Reactivity
Application
Application Details
-
IHC: 1/100-1/500
Immunogen
-
Synthesized peptide derived from human Desmin
Molecular Weight
-
-
Formulation
-
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
-
Liquid
Gene ID
-
1674
Uniprot ID
-
P17661
Background
-
Desmin a class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Research Area
-
Cell Biology
Synonyms
-
DES; Desmin