Anti-DDX56 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
DDX56
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
ZN152
Isotype
-
IgG1
Reactivity
Application
Application Details
-
IHC: 1/50-1/100
Immunogen
-
Human recombinant protein fragment of human DDX56 (NP_061955) produced in E.coli.
Molecular Weight
-
-
Formulation
-
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
-
Liquid
Gene ID
-
54606
Uniprot ID
-
Q9NY93
Background
-
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
DDX21; DDX26; NOH61; Probable ATP-dependent RNA helicase DDX56; ATP-dependent 61 kDa nucleolar RNA helicase; DEAD box protein 21; DEAD box protein 56