Anti-DDOST Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
DDOST
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000
Immunogen
-
Fusion protein of human DDOST
Molecular Weight
-
Calculated MW: 51 kDa; Observed MW: 51 kDa
Formulation
-
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
-
Liquid
Gene ID
-
1650
Uniprot ID
-
P39656
Background
-
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Research Area
-
Tags & Cell Markers
Synonyms
-
OST; WBP1; AGER1; CDG1R; OST48; OKSWcl45