Anti-DDB1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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DDB1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-2A3
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
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A synthetic peptide of human DDB1
Molecular Weight
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Calculated MW: 127 kDa; Observed MW: 127 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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1642
Uniprot ID
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Q16531
Background
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Required for DNA repair. Binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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XPE; DDBA; XAP1; XPCE; XPE-BF; UV-DDB1