Anti-DCP1A Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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DCP1A
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human DCP1A
Molecular Weight
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Calculated MW: 63 kDa; Observed MW: 63 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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55802
Uniprot ID
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Q9NPI6
Background
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Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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SMIF; SMAD4IP1; HSA275986; Nbla00360