Anti-Cytokeratin 17 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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KRT17
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-7A3
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human Cytokeratin 17
Molecular Weight
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Calculated MW: 48 kDa; Observed MW: 48 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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3872
Uniprot ID
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Q04695
Background
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Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair.
Research Area
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Signal Transduction
Synonyms
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Keratin; type I cytoskeletal 17; Cytokeratin-17; CK-17; Keratin-17; K17