Anti-Cytokeratin 17 (8C6) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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KRT17
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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8C6-4H2-5C1
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
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Synthetic Peptide of CK17
Molecular Weight
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Calculated MW: 48 kDa; Observed MW: 48 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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3872
Uniprot ID
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Q04695
Background
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Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair.
Research Area
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Signal Transduction
Synonyms
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Keratin; type I cytoskeletal 17; Cytokeratin-17; CK-17; Keratin-17; K17