Anti-Cytochrome P450 11A1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CYP11A1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Fusion protein of human CYP11A1
Molecular Weight
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Calculated MW: 60 kDa; Observed MW: 60 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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1583
Uniprot ID
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P05108
Background
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
Research Area
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Cardiovascular
Synonyms
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cytochrome P450; family 11; subfamily A; polypeptide 1; CYP11A; CYPXIA1; P450SCC