Anti-Cystatin C Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CST3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human Cystatin C
Molecular Weight
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Calculated MW: 16 kDa; Observed MW: 16 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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1471
Uniprot ID
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P01034
Background
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Cystatin C is a 14 kDa member of the Cystatin superfamily of cysteine protease inhibitors. Most cell types secrete Cystatin C. Cystatin C inhibits cathepsins, and thereby may function as a tumor suppressor by inhibiting cathepsin mediated tumor cell invasion. In addition, this tumor suppressor function can also be attributed to Cystatin C's ability to antagonize TGF-β1 signaling.
Research Area
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Tags & Cell Markers
Synonyms
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CST3; Cystatin-C; Cystatin-3; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin